Selank

99%+ Purity USA Tested

Research Use Only. Not for Human or Veterinary Use

Selank: Synthetic heptapeptide (tuftsin analog), CAS 129954-34-3, MW 751.87 g/mol, ≥99% purity. Lyophilized powder for laboratory use.

$50.00

10 in stock

Peptide Name	Selank (TP-7)
CAS Number	129954-34-3
Molecular Formula	C₃₃H₅₇N₁₁O₉
Molecular Weight	751.87 g/mol
Sequence	Thr-Lys-Pro-Arg-Pro-Gly-Pro
Appearance	White lyophilized powder
Purity	≥99% (HPLC)
Storage	-20°C, desiccated, protected from light
Solubility	Soluble in sterile water

This product is not intended for human or animal use. For scientific research only.

VivePeptides provides detailed analytical results including High-Performance Liquid Chromatography (HPLC) and mass spectrometry data for all peptides. These reports confirm peptide purity, composition, and molecular accuracy, giving researchers full transparency and confidence in the materials used for their studies.

VIEW COA

VivePeptides peptides should be stored in a cool, dry environment and protected from light and moisture. Lyophilized peptides are best kept refrigerated or frozen until use to maintain stability. Once reconstituted for research purposes, peptides should be stored according to standard laboratory protocols, typically under refrigeration, and handled using proper aseptic techniques to preserve integrity throughout the study period.

OVERVIEW

What Is Selank Peptide?

Selank is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is based on the naturally occurring tetrapeptide tuftsin (Thr-Lys-Pro-Arg), which is a fragment of the immunoglobulin G heavy chain with known immunomodulatory properties. The selank peptide extends tuftsin’s sequence with a Pro-Gly-Pro C-terminal addition, which enhances metabolic stability and adds novel biological properties to the parent compound.

Classified as a nootropic and anxiolytic research peptide, selank research has focused on its interactions with neurotransmitter systems, immune function pathways, and gene expression in the central nervous system. Selank nootropic research has demonstrated effects on GABA, serotonin, and dopamine systems in preclinical models, while selank anxiety research has documented behavioral effects in standard animal anxiety models. Researchers who buy selank online from VivePeptides receive a compound manufactured to selank 99% purity standards by a trusted USA supplier.

Nootropic Heptapeptide

Synthetic tuftsin analog with anxiolytic and immunomodulatory research properties

≥99% HPLC Purity

Every batch verified via high-performance liquid chromatography

USA Tested & Verified

Third-party analytical testing performed in USA laboratories

RESEARCH

Selank Mechanism of Action in Research

The selank mechanism of action involves complex interactions with multiple neurotransmitter systems and immune signaling pathways. Selank research has revealed that this peptide influences brain chemistry through several interconnected mechanisms.

GABAergic System Modulation

Selank research has demonstrated significant interactions with the GABAergic system, the primary inhibitory neurotransmitter network in the central nervous system. Studies indicate that selank may enhance GABA-mediated inhibitory neurotransmission by modulating GABA receptor sensitivity. Published research suggests selank influences the expression of GABA receptor subunit genes in specific brain regions, potentially underlying its observed anxiolytic-like effects in animal behavioral models (Seredenin & Gudasheva, CNS Neuroscience & Therapeutics, 2013).

Serotonergic and Monoamine Pathway Interactions

Selank anxiety research has documented the peptide’s interactions with the serotonergic system. Studies in rodent models indicate that selank may influence serotonin metabolism and 5-HT receptor expression in brain regions associated with emotional regulation. Additionally, selank research has shown effects on dopamine and norepinephrine metabolism, suggesting a broad influence on monoamine neurotransmitter systems.

Immunomodulatory Pathways

Drawing from its tuftsin heritage, selank research has also explored immunomodulatory mechanisms. Studies indicate selank may influence the expression of interleukins and other cytokines, potentially modulating immune response patterns. This dual neuro-immune research profile distinguishes selank from many single-pathway nootropic peptides. —

COMPARISON

Selank vs Semax: Research Peptide Comparison

Selank and semax are both Russian-developed synthetic peptides studied in nootropic and neuroscience research. While they share overlapping research contexts, they differ in origin, structure, and proposed primary mechanisms.

Feature	Selank	Semax
Origin	Tuftsin analog (IgG fragment-derived)	ACTH(4-10) analog
CAS Number	129954-34-3	80714-61-0
Amino Acids	7	7
Molecular Weight	751.87 Da	813.93 Da
Primary Research Focus	Anxiolytic and immunomodulatory research	Cognitive and neurotrophic research
Key Neurotransmitter Target	GABAergic system	BDNF/neurotrophic pathways
Immune Activity	Documented immunomodulatory effects	Limited immune research
Parent Peptide	Tuftsin (Thr-Lys-Pro-Arg)	ACTH(4-10)

Both selank and semax are available from VivePeptides at ≥99% purity. Researchers studying anxiolytic mechanisms and neuro-immune interactions often choose selank, while those focused on BDNF expression and cognitive pathways may prefer semax.

RESEARCH STUDIES

Selank Research Applications & Published Studies

Selank research spans two decades of published literature, with studies conducted primarily at Russian research institutions and expanding internationally.

Anxiolytic Research Models

Selank anxiety research includes numerous studies using established behavioral paradigms. Seredenin & Gudasheva (CNS Neuroscience & Therapeutics, 2013) reviewed selank’s effects across multiple anxiety models, including the elevated plus maze and light-dark box tests in rodents. Published data indicate that selank produces measurable effects on anxiety-related behaviors in these standard preclinical models without the sedation commonly observed with GABAergic compounds.

Gene Expression and Neurotrophic Factor Studies

Selank research has included genomic studies examining its effects on gene expression in brain tissue. Published microarray data indicate that selank may modulate the expression of genes involved in neurotrophic signaling, synaptic plasticity, and inflammatory response. Studies have documented selank’s influence on BDNF, NGF, and related gene expression in specific brain regions of rodent models.

Immunological Research

Building on tuftsin’s known immunomodulatory properties, selank research has explored immune function effects. Published studies have documented selank’s influence on cytokine expression patterns, including IL-6, IL-10, and TNF-α, in various experimental immune models. This immunomodulatory research profile makes selank unique among nootropic research peptides.

QUALITY ASSURANCE

Quality & Testing Standards

HPLC & Mass Spectrometry

Every selank batch undergoes HPLC and mass spectrometry analysis to verify peptide identity, sequence accuracy, and purity.

Third-Party Verified

All selank is independently tested at third-party USA-based analytical laboratories with complete documentation.

≥99% Purity Standard

VivePeptides selank consistently meets or exceeds ≥99% purity as verified by HPLC for reliable research results.

FAQ

Frequently Asked Questions About Selank

What is selank used for in research?

Selank is used in preclinical research to study anxiolytic mechanisms, GABAergic neurotransmission, serotonergic pathway modulation, immunomodulatory signaling, and nootropic peptide biology. Selank is sold for research use only.

What purity is VivePeptides selank?

VivePeptides selank peptide is manufactured to ≥99% purity as verified by HPLC. Every batch is independently tested at USA-based analytical laboratories.

How should selank be stored?

Lyophilized selank should be stored at -20°C, protected from light and moisture. Reconstituted solutions should be stored at 2–8°C and used within 14 days.

What is the relationship between selank and tuftsin?

Selank was designed as a stabilized analog of tuftsin, a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) found as a fragment of the immunoglobulin G heavy chain. Selank retains tuftsin’s sequence and extends it with a Pro-Gly-Pro C-terminal tail that enhances metabolic stability and introduces additional neurotrophic properties.

Is VivePeptides selank third-party tested?

Yes. Every lot of VivePeptides selank undergoes independent third-party testing at USA-based laboratories, including HPLC purity analysis and mass spectrometry identity verification. Results are available for qualified researchers.

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